A curtain-wall system for a building comprises a plurality of prefabricated cells (2), wherein each cell (2) includes:a structural frame (10) with at least two uprights (11) and two end cross members (12), coupled together to form a perimetral structure that delimits an opening (V);one or more infill elements (14-16) associated to the structural frame (10) at a front thereof, for closing the opening (V) delimited by the perimetral structure; andinterface sectional elements (20, 21; 70-72) for coupling the one or more infill elements (14-16) to the front of the structural frame (10).