A twist action mixing container is capable of separately storing various substances for later mixing. The mixing container includes an upper and lower housing which respectively define an upper and lower chamber. The upper and lower chambers are separated by a valve assembly that seals off one chamber from the other until the valve assembly is opened. The valve assembly includes upper and lower valve halves, each of which includes one or more tracks along their periphery and corresponding guide members that insert into said tracks. When the upper and lower housings are twisted in opposite directions, the guide members travel along their respective tracks moving upper and lower valve openings into alignment, thus opening the valve assembly. A preventer is operably coupled to the lower valve for blocking the container opening while the valve assembly is closed.