Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
December 22, 2015
Patent Application Number
13952040
Date Filed
July 26, 2013
Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided herein are methods for generation and amplification of a single-stranded DNA circle in a single reaction vessel from a linear DNA without any intervening purification steps. The single-stranded DNA circle is generated via a template-independent single-stranded DNA ligation. Whole-genome amplification of circulating nucleic acids extracted from blood is provided. Kits for performing the disclosed methods are also provided.
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