US Patent 9220677 Methods and compositions for CNS delivery of iduronate-2-sulfatase
Patent 9220677 was granted and assigned to Shire (pharmaceutical company) on December, 2015 by the United States Patent and Trademark Office.
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Patent abstract
The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an iduronate-2-sulfatase (I2S) protein, salt, and a polysorbate surfactant for the treatment of Hunters Syndrome.
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US Patent 09220677 Methods and compositions for CNS delivery of iduronate-2-sulfatase US Patent 9220677 Methods and compositions for CNS delivery of iduronate-2-sulfatase
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Patent Number
092206770
Patent Number
92206770
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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
092206770
Date of Patent
December 29, 2015
0Patent Application Number
139744570
Date Filed
August 23, 2013
0Official Website
Patent Primary Examiner
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US Patent 09220677 Methods and compositions for CNS delivery of iduronate-2-sulfatase
Infobox
Is a
Patent applicant
Current assignee
Patent jurisdiction
Patent number
09220677
Date of patent
December 29, 2015
Patent application number
13974457
Date Filed
August 23, 2013
Patent primary examiner
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