Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jean-François Prost0
Christine Gaucher0
Christophe De Romeuf0
Jean-Luc Teillaud0
Date of Patent
January 12, 2016
0Patent Application Number
117931380
Date Filed
December 14, 2005
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention is directed to a monoclonal antibody directed against CD20 antigen, for therapeutic administration to humans, wherein each of the light chains of the antibody is encoded by murine-human chimeric nucleic acid sequence SEQ ID No. 27, and each of the heavy chains of the antibody is encoded by murine-human chimeric nucleic acid sequence SEQ ID No. 19. The invention is further directed to methods of in vitro activation of FcγRIIIA receptors in immune effector cells with the antibody and methods of treating CD20-expressing leukaemia or lymphoma with the antibody.
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