A clamping device (1) for a machine tool (2) for machining at least one dental workpiece (3), wherein the clamping device (1) has at least one workpiece carrier (4) for accommodating the dental workpiece (3) during machining, wherein at least one tool holder (5) for holding at least one, preferably a plurality of cutting tools (6) for machining the dental workpiece (3) is arranged, preferably fixedly, on the workpiece carrier (4), and the workpiece carrier (4) and the tool holder (5) are fastened or fastenable together as one component on a carrier of the clamping device (1) in an exchangeable manner by a fastening device (7) that is non-destructively releasable, preferably without a tool.