Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kallanthottathil G. Rajeev0
Martin Maier0
Muthiah Manoharan0
Tracy Zimmermann0
Kevin Fitzgerald0
Date of Patent
March 22, 2016
0Patent Application Number
138224410
Date Filed
September 14, 2011
0Patent Citations Received
0
0
...
Patent Primary Examiner
Patent abstract
The present invention provides effective motifs for RNA agents conjugated to at least one ligand, which are advantageous for the in vivo delivery of iRNA duplex agents. Additionally, the present invention provides methods of making these compositions, as well as methods of introducing these iRNA duplex agents into cells using these compositions, e.g., for the treatment of various disease conditions.
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