Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Derek O'Hagan0
Andrew Geall0
Luis Brito0
Manmohan Singh0
Date of Patent
March 29, 2016
Patent Application Number
13235454
Date Filed
September 18, 2011
Patent Citations Received
...
Patent Primary Examiner
Patent abstract
This invention generally relates to cationic oil-in-water emulsions that can be used to deliver negatively charged molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are particularly suitable for delivering nucleic acid molecules (such as an RNA molecule encoding an antigen) to cells and formulating nucleic acid-based vaccines.
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