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US Patent 9301996 Modified beta-lactamases and methods and uses related thereto

Patent 9301996 was granted and assigned to Synthetic Biologics, Inc. on April, 2016 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Synthetic Biologics, Inc.
Synthetic Biologics, Inc.
Current Assignee
Synthetic Biologics, Inc.
Synthetic Biologics, Inc.
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9301996
Date of Patent
April 5, 2016
Patent Application Number
14676559
Date Filed
April 1, 2015
Patent Primary Examiner
‌
Robert Mondesi
Patent abstract

The present invention relates to pharmaceuticals and modified beta-lactamases. Specifically, the invention relates to novel recombinant beta-lactamases and pharmaceutical compositions comprising the beta-lactamases. Also, the present invention relates to methods for modifying a beta-lactamase, producing the beta-lactamase and treating or preventing beta-lactam antibiotic induced adverse effects. Furthermore, the present invention relates to the beta-lactamase for use as a medicament and to the use of the beta-lactamase in the manufacture of a medicament for treating or preventing beta-lactam antibiotics induced adverse effects. Still further, the invention relates to a polynucleotide and a host cell comprising the polynucleotide.

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