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US Patent 9309282 Solid phase for mixed-mode chromatographic purification of proteins

Patent 9309282 was granted and assigned to Bio-Rad Laboratories on April, 2016 by the United States Patent and Trademark Office.

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Patent abstract

Proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of no more than three atoms between the hydrophobic group and the support matrix.

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