The present invention provides improved thermally insulative containers (e.g., ice chests, coolers, lunch boxes, etc.) that include one or more isolation compartment(s) that may be isolated from a storage compartment holding ice or other cooling agent(s). The isolation compartment may be used to store items that are to be kept dry and at a higher temperature than food, beverages, and other items that are typically kept in the storage compartment. In some examples, the one or more isolation compartment(s) may include thermal vents between the compartments for varying the temperature between the one or more isolation compartment(s) and the storage compartment.