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US Patent 9321808 Homo- and heterodimeric SMAC mimetic compounds as apoptosis inducers

Patent 9321808 was granted and assigned to BioNTech on April, 2016 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
BioNTech
BioNTech
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9321808
Patent Inventor Names
Pierfausto Seneci0
Daniele Lecis0
Domenico Delia0
Eloise Mastrangelo0
Federica Cossu0
Francesca Vasile0
Laura Belvisi0
Carmelo Drago0
...
Date of Patent
April 26, 2016
Patent Application Number
14379675
Date Filed
February 20, 2012
Patent Citations Received
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US Patent 11911643 Environmentally-clean fire inhibiting and extinguishing compositions and products for sorbing flammable liquids while inhibiting ignition and extinguishing fire
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US Patent 11654313 Wireless communication network, GPS-tracked ground-based spraying tanker vehicles and command center configured for proactively spraying environmentally-safe anti-fire chemical liquid on property surfaces to inhibit fire ignition and flame spread in the presence of wild fire
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US Patent 11654314 Method of managing the proactive spraying of environment ally-clean anti-fire chemical liquid on GPS-specified property surfaces so as to inhibit fire ignition and flame spread in the presence of wild fire
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US Patent 11697039 Wireless communication network, GPS-tracked back-pack spraying systems and command center configured for proactively spraying environmentally-safe anti-fire chemical liquid on property surfaces to inhibit fire ignition and flame spread in the presence of wild fire
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US Patent 11697040 Wild fire defense system network using a command center, spraying systems and mobile computing systems configured to proactively defend homes and neighborhoods against threat of wild fire by spraying environmentally-safe anti-fire chemical liquid on property surfaces before presence of wild fire
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US Patent 11697041 Method of proactively defending combustible property against fire ignition and flame spread in the presence of wild fire
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US Patent 11707639 Wireless communication network, GPS-tracked mobile spraying systems, and a command system configured for proactively spraying environmentally-safe anti-fire chemical liquid on combustible property surfaces to protect property against fire ignition and flame spread in the presence of wild fire
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US Patent 11865390 Environmentally-clean water-based fire inhibiting biochemical compositions, and methods of and apparatus for applying the same to protect property against wildfire
0
...
Patent Primary Examiner
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Bruck Kifle
Patent abstract

The present invention relates to conformationally constrained homo- and heterodimeric mimetics of Smac with function as inhibitors of Inhibitor of Apoptosis Proteins (IAPs), the invention also relates to the use of these compounds in therapy, wherein the induction of apoptotic cell death is beneficial, especially in the treatment of cancer, alone or in combination with other active ingredients.

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