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Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Maria Beatriz Herrera Sanchez0
Benedetta Bussolati0
Giovanni Camussi0
Stefano Buttiglieri0
Date of Patent
May 10, 2016
0Patent Application Number
119210300
Date Filed
May 24, 2006
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates to human liver pluripotent progenitor cell lines which express hepatic cell markers such as albumin and α-fetoprotein and do not express some of the markers which are typical of oval stem cells. Also disclosed is a method of isolating the cell lines of the invention, methods for differentiating said cells into a plurality of different cell lineages, methods for conditional immortalization and metabolic selection of said cells, as well as the use of the cell lines of the invention for preparing a medicament with osteogenic differentiation activity or liver injury regeneration activity.
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