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US Patent 9352048 Carbohydrate conjugates as delivery agents for oligonucleotides

Patent 9352048 was granted and assigned to Alnylam Pharmaceuticals on May, 2016 by the United States Patent and Trademark Office.

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Patent

Patent attributes

Patent Applicant

Alnylam Pharmaceuticals

Current Assignee

Alnylam Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

9352048

Date of Patent

May 31, 2016

Patent Application Number

14338161

Date Filed

July 22, 2014

Patent Citations Received

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US Patent 12121592 Lipid nanoparticle compositions and methods for mRNA delivery

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US Patent 12060381 Methods for purification of messenger RNA

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US Patent 12084702 Methods for purification of messenger RNA

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US Patent 12116573 Targeting ligands for therapeutic compounds

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US Patent 11692189 Methods for purification of messenger RNA

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US Patent 11712463 MRNA therapy for pompe disease

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US Patent 11879125 GalNAc compositions for improving siRNA bioavailability

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US Patent 11884692 Methods for purification of messenger RNA

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Patent Primary Examiner

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Patrick Lewis

Patent abstract

The present invention provides iRNA agents comprising at least one subunit of the formula (I):

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