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US Patent 9370581 Carbohydrate conjugates as delivery agents for oligonucleotides

Patent 9370581 was granted and assigned to Alnylam Pharmaceuticals on June, 2016 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Patent Applicant

Alnylam Pharmaceuticals

Current Assignee

Alnylam Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

93705810

Patent Inventor Names

Martin Maier0

Jayaprakash Nair0

Kallanthottathil G. Rajeev0

Muthiah Manoharan0

Date of Patent

June 21, 2016

Patent Application Number

143295400

Date Filed

July 11, 2014

Patent Citations Received

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US Patent 12059468 Carbohydrate conjugates as delivery agents for oligonucleotides

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US Patent 11666653 Carbohydrate conjugates as delivery agents for oligonucleotides

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US Patent 11712463 MRNA therapy for pompe disease

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US Patent 11944687 Carbohydrate conjugate RNA agents and process for their preparation

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US Patent 11998601 Messenger RNA therapy for treatment of articular disease

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US Patent 12016954 CNS delivery of mRNA and uses thereof

Patent Primary Examiner

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Patrick Lewis

Patent abstract

The present invention provides iRNA agents comprising at least one subunit of the formula (I):

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