Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Sebastien Deshayes0
Gilles Divita0
Karidia Konate0
May Catherine Morris0
Date of Patent
June 28, 2016
0Patent Application Number
140096480
Date Filed
April 4, 2012
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The présent invention relates to cell-penetrating peptides char-acterized in that it comprises an amino acid séquence selected in the group consisting of X1LX2RALWX9LX3X9X4LWX9LX5X6X7X8, X1LX2LARWX9LX3X9X4LWX9LX5X6X7X8 and X1LX2ARLWX9LX3X9X4LWX9LX5X6X7X8, wherein X1 is beta-A or S, X2 is F or W, X3 is L, W, C or I, X4 is S, A, N or T, Xs is L or W, X6 is W or R, X7 is K or R, X8 is A or none, and X9 is R or S. Thèse peptides exhibit high efficiency, low toxicity and a natural tropism for lung tissues, and can be used either in simple complex with the cargo to be vectorised, or in nanoparticles comprising two layers of cell-penetrating peptides around the cargo.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.