Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Andreas Loew0
John Scholler0
Laura Alexandra Johnson0
Marcela Maus0
Carl H. June0
Hideho Okada0
Jennifer Brogdon0
Date of Patent
July 19, 2016
Patent Application Number
14184924
Date Filed
February 20, 2014
Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention provides compositions and methods for treating diseases associated with expression of EGFRvIII. The invention also relates to chimeric antigen receptor (CAR) specific to EGFRvIII, vectors encoding the same, and recombinant T cells comprising the anti-EGFRvIII CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises an anti-EGFRvIII binding domain.
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