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US Patent 9402875 Amidated dopamine neuron stimulating peptide restoration of mitochondrial activity

Patent 9402875 was granted and assigned to University of Kentucky on August, 2016 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to the use of novel proteins, referred to herein as amidated glial cell line-derived neurotrophic factor (GDNF) peptides (or “Amidated Dopamine Neuron Stimulating peptides (ADNS peptides)”), for treating brain diseases and injuries that result in dopaminergic deficiencies and mitochodrial dysfunction, e.g., reduced complex I enzyme activity.

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