Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tannin A. Schmidt0
David A. Sullivan0
Benjamin Sullivan0
Date of Patent
August 23, 2016
Patent Application Number
14831317
Date Filed
August 20, 2015
Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided herein are ophthalmically acceptable pharmaceutical compositions comprising PRG4 or lubricant fragments and a PRG4 inducing compound. The PRG4 inducing compound in the pharmaceutical composition of the present invention upregulates PRG4 expression and localization in the ocular surface for efficient surface boundary lubrication. In some instances, pharmaceutical compositions described herein are utilized for treating ophthalmic conditions, e.g., ocular boundary deficiency and symptoms associated therewith.
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