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US Patent 9422368 Humanized anti-human NKG2A monoclonal antibody

Patent 9422368 was granted and assigned to Novo Nordisk on August, 2016 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Jinchao Zhang0

Jianhe Chen0

Jing Su0

Jiujiu Yu0

Petrus Johannes Louis Spee0

Soren Berg Padkjaer0

Date of Patent

August 23, 2016

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Patent Application Number

144493460

Date Filed

August 1, 2014

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Patent Citations Received

US Patent 12129485 Blockade of CD2 surface expression and expression of chimeric antigen receptors for immunotherapy of T-cell malignancies

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US Patent 12012450 Anti-NKG2A antibodies and compositions

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US Patent 11981734 Nucleic acid molecules encoding antibodies which bind natural killer cell inhibitory receptor group 2A protein (NKG2A)

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US Patent 12077584 Methods of treating HLA-E-expressing cancers by administering antibodies which bind human natural killer cell inhibitory receptor group 2A (NKG2A)

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US Patent 11976125 B cell maturation antigen binding proteins

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US Patent 12084518 Trispecific binding proteins and methods of use

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Patent Primary Examiner

Zachary Skelding

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Patent abstract

The present invention relates to agents that are non-competitive antagonists of the CD94/NKG2A receptor such as certain anti-NKG2A antibodies, in particular humanized versions of murine anti-NKG2A antibody Z199, as well as methods of producing and using such agents and antibodies.

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