Methods and systems provide an integrated display, on a single screen, of images obtained from multiple modalities used in screening a subject. The methods and systems are usable with 2D, 3D, and 4D imaging, by which a single screen displays a screen image from a first modality. A window delineating an area of interest is placed on a first modality image from the first modality, and this area of interest is then displayed on a second modality image from a second modality, thereby providing a combined image representing the area of interest through both modalities. Preferably, the first modality image corresponds and/or is correlated with the second modality image.