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US Patent 9464140 Compositions and methods for treatment of cancer

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Michael D. Kalos0

Bruce L. Levine0

Carl H. June0

David L. Porter0

Michael C. Milone0

Date of Patent

October 11, 2016

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Patent Application Number

149969530

Date Filed

January 15, 2016

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Patent Citations Received

US Patent 11952428 BCMA chimeric antigen receptors and uses thereof

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US Patent 12076375 Treating and preventing

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US Patent 11680103 Compositions and methods for treating cancer with anti-CD19/CD20 immunotherapy

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US Patent 11701384 Methods and compositions involving interleukin-6 receptor alpha-binding single chain variable fragments

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US Patent 11759480 Compositions and methods for CAR T cell therapy

US Patent 11965012 Compositions and methods for TCR reprogramming using fusion proteins

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US Patent 11779602 Methods of use for CAR T cells

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Patent Primary Examiner

Michael Burkhart

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Patent abstract

The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.

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