Patent 9469676 was granted and assigned to Bristol-Myers Squibb on October, 2016 by the United States Patent and Trademark Office.
The application provides Fc fusion proteins having novel arrangements. In one embodiment, the application provides Fc fusion proteins comprising a 10Fn3 domain. In another embodiment, the application provides Fc fusion proteins comprising linkers derived from the naturally occurring C-terminal tail regions of membrane bound or secretory immunoglobulins.