Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 8, 2016
Patent Application Number
14857308
Date Filed
September 17, 2015
Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives.
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