Patent 9493813 was granted and assigned to Beth Israel Deaconess Medical Center on November, 2016 by the United States Patent and Trademark Office.
The invention features methods for identifying compounds that modulate the activity of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K). Inhibitors of PI5P4K can be used in, for example, the treatment or prevention of cell proliferation disorders (e.g., the prevention of tumor cell growth in p53 mutated cancers).