Patent 9499810 was granted and assigned to aTyr Pharma on November, 2016 by the United States Patent and Trademark Office.
Thrombopoietic compositions are provided comprising tyrosyl tRNA synthetase polypeptides, including truncations and/or variants thereof. Also provided are methods of using such compositions in the treatment of conditions that benefit from increased thrombopoiesis, such as thrombocytopenia.