Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Marc Wehrli0
Sylvia Miescher0
Adrian Zürcher0
Stephan Von Gunten0
Date of Patent
December 20, 2016
0Patent Application Number
139918110
Date Filed
December 14, 2011
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis.
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