The present application is directed to closure assemblies, and particularly closure assemblies for closing an opening in a vessel. In particular embodiments, the closure assemblies described herein can have a first ring having a top surface, an inner surface and an outer surface, wherein the outer surface comprises threading, wherein the first ring comprises a first flange having a top surface extending radially inward from the inner surface of the first ring a distance of FL, and wherein the top surface of the first flange is spaced apart from the top surface of the first ring by a distance FH, and wherein a ratio of FH:FL is greater than 1.