Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Dai Wang0
Tong-Ming Fu0
Muneeswara Babu Medi0
Date of Patent
January 17, 2017
0Patent Application Number
143436370
Date Filed
September 4, 2012
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to methods of inducing an immune response to cytomegalovirus (CMV) using a genetically modified CMV that is conditionally replication defective. The methods of the invention can be used to treat and/or prevent primary CMV infection, infection due to reactivation of a latent CMV and a super-infection of a different strain of CMV that had been previously encountered. The present invention also relates to a replication defective CMV which has been recombinantly altered to allow for external control of viral replication. Compositions comprising the replication defective CMV are also encompassed by the present invention.
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