Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Harald Rau0
Torben Lessmann0
Date of Patent
February 7, 2017
0Patent Application Number
135741200
Date Filed
January 21, 2011
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof, comprising a drug linker conjugate D-L, wherein D being a biologically active moiety containing an aromatic hydroxyl group is conjugated to one or more polymeric carriers via secondary carbamate-containing linkers L. Such carrier-linked prodrugs achieve drug releases with therapeutically useful half-lives. The invention also relates to pharmaceutical compositions comprising said prodrugs and their use as medicaments.
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