Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Minh-Ha Do0
Kyle Chiang0
Marc Thomas0
Ying Buechler0
Chi-Fang Wu0
Darin Lee0
Jeffry D. Watkins0
John D. Mendlein0
...
Date of Patent
March 7, 2017
0Patent Application Number
142144910
Date Filed
March 14, 2014
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides histidyl-tRNA synthetase and Fc region conjugate polypeptides (HRS-Fc conjugates), such as HRS-Fc fusion polypeptides, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The HRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified HRS polypeptides.
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