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US Patent 9611499 Method for producing soluble recombinant interferon protein without denaturing

Patent 9611499 was granted and assigned to Pfenex Inc on April, 2017 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
‌
Pfenex Inc
Current Assignee
‌
Pfenex Inc
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9611499
Date of Patent
April 4, 2017
Patent Application Number
14884081
Date Filed
October 15, 2015
Patent Primary Examiner
‌
Robert Landsman
Patent abstract

The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to extraction of soluble, active recombinant protein from an insoluble fraction without the use of denaturation and without the need for a refolding step. In particular, the present invention relates to a production process for obtaining high levels a soluble recombinant Type 1 interferon protein from a bacterial host.

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