Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
April 11, 2017
Patent Application Number
14815917
Date Filed
July 31, 2015
Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates to N-hydroxylsulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxylsulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxylsulfonamide derivatives.
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