US Patent 9624290 Lowered affinity antibodies and methods of making the same
Patent 9624290 was granted and assigned to AB Biosciences on April, 2017 by the United States Patent and Trademark Office.
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Patent abstract
The present invention provides methods for making novel, rationally designed lowered affinity antibodies. The methods of the present invention make antibodies that have variable domains that have been designed to reduce or eliminate the antigen binding activity of the parental antibody without altering the overall (3) dimensional antibody structure. Using the antibodies made using methods of the present invention in various assays allows researchers to distinguish effects that result from specific antigen-antibody interactions from other, non-specific antibody effects.
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Patent Inventor Names
Hsiu-Ching Chang0
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US Patent 09624290 Lowered affinity antibodies and methods of making the same US Patent 9624290 Lowered affinity antibodies and methods of making the same
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Patent Number
096242900
Patent Number
96242900
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Patent Jurisdiction
Patent Number
096242900
Date of Patent
April 18, 2017
0Patent Application Number
135752190
Date Filed
January 28, 2011
0Official Website
Patent Primary Examiner
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US Patent 09624290 Lowered affinity antibodies and methods of making the same
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Is a
Current assignee
Patent jurisdiction
Patent number
09624290
Date of patent
April 18, 2017
Patent application number
13575219
Date Filed
January 28, 2011
Patent primary examiner
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