Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael Heartlein0
Frank DeRosa0
Yizhou Dong0
Daniel Anderson0
Date of Patent
April 25, 2017
0Patent Application Number
145211610
Date Filed
October 22, 2014
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides, among other things, methods of delivering mRNA in vivo, including administering to a subject in need of delivery a composition comprising an mRNA encoding a protein, encapsulated within a liposome such that the administering of the composition results in the expression of the protein encoded by the mRNA in vivo, wherein the liposome comprises a cationic lipid of formula I-c:
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