A vehicle computer is programmed to determine an expected thermal load for an autonomous driving compute cluster and a target temperature for the compute cluster under the expected thermal load. Based on a comparison of a current temperature of the compute cluster to an ambient temperature, the vehicle computer is further programmed to operate a switching valve in a first coolant path to open the path to one of a radiator portion and a condenser portion and operate, with the path open to the condenser portion, a pump in the first coolant path and a condenser in a second coolant path at speeds respectively based on at least one of the expected thermal load and the target temperature.