Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
June 6, 2017
Patent Application Number
14790562
Date Filed
July 2, 2015
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing a mRNA solution and a lipid solution, wherein the mRNA solution and/or the lipid solution are at a pre-determined temperature greater than ambient temperature.
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