Techniques to manage applications, such as mobile apps, across multiple management domains are disclosed. In various embodiments, a set of one or more application management policies to be enforced with respect to a mobile device is received from a management entity to which a scope of authority to manage applications with respect to the mobile device has been delegated. A management agent on the mobile device is used to enforce the one or more application management policies with respect to applications and application data that are within the scope of authority delegated to the management entity.