Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ying Ji Buechler0
Chi-Fang Wu0
Jeffrey D. Watkins0
John D. Mendlein0
Ryan Andrew Adams0
Date of Patent
June 27, 2017
0Patent Application Number
143687590
Date Filed
December 27, 2012
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides aspartyl-tRNA synthetase and Fc region conjugate polypeptides (DRS-Fc conjugates), such as DRS-Fc fusion proteins, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The DRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified DRS polypeptides.
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