Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ying Ji Buechler0
Jeffrey D. Watkins0
John D. Mendlein0
Ryan Andrew Adams0
Chi-Fang Wu0
Date of Patent
June 27, 2017
0Patent Application Number
143687590
Date Filed
December 27, 2012
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides aspartyl-tRNA synthetase and Fc region conjugate polypeptides (DRS-Fc conjugates), such as DRS-Fc fusion proteins, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The DRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified DRS polypeptides.
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