Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Peter Sportelli0
Hari P. Miskin0
Michael S. Weiss0
Swaroop K. V. S. Vakkalanka0
Date of Patent
July 4, 2017
Patent Application Number
14440139
Date Filed
November 1, 2013
Patent Citations Received
Patent Primary Examiner
Patent abstract
Highly effective combinations of a compound of formula A (a PI3Kδ selective inhibitor) and anti-CD20 antibodies are provided herein for the treatment and amelioration of PI3Kδ and/or CD20 mediated diseases and disorders. In particular, the combination can be used to treat cancers and autoimmune diseases. More particularly, the invention provided for a combination of a compound of formula A, or stereoisomers thereof, and ublituximab for the treatment and/or amerioration of hematological malignancies such as leukemia and lymphoma.
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