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US Patent 9696310 Molecular sensor and methods of use thereof

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Linor Unger0

David Margulies0

Leila Motiei0

Date of Patent

July 4, 2017

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Patent Application Number

147388940

Date Filed

June 14, 2015

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Patent Citations Received

US Patent 12018159 Ultra bright dimeric or polymeric dyes and methods for preparation of the same

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US Patent 12006438 Polymeric dyes with linker groups comprising deoxyribose

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US Patent 11874280 Use of divalent metals for enhancement of fluorescent signals

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US Patent 11939474 Water soluble fluorescent or colored dyes and methods for their use

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US Patent 11931419 Programmable polymeric drugs

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US Patent 11945955 Polymeric tandem dyes with linker groups

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US Patent 11981820 Ultra bright dimeric or polymeric dyes

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US Patent 12076407 Polymers with rigid spacing groups comprising biologically active compounds

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Patent Primary Examiner

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Patent abstract

The present invention is directed to fluorescent molecular sensor based on Thiazole Orange for protein detection. Interaction of the protein target with the molecular sensors of this invention results in a significant increase in the fluorescence emission. The generation of light output signal enables one to detect protein biomarkers associated with different diseases or detecting the protein of interest also in living cells.

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