Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Micha A. Häuptle0
Manuela Mally0
Michael L. Wetter0
Michael T. Kowarik0
Stefan J. Kemmler0
Veronica Gambillara0
Date of Patent
July 11, 2017
0Patent Application Number
146288440
Date Filed
February 23, 2015
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided herein is a novel E. coli O polysaccharide, O25B. Also provided herein are prokaryotic host cells comprising enzymes (e.g., glycosyltransferases) used in O25B production. The host cells provided herein produce O25B bioconjugates, wherein said bioconjugates comprise O25B linked to a carrier protein. Further provided herein are compositions, e.g., pharmaceutical compositions, comprising O25B and/or bioconjugates comprising O25B. Such compositions can be used as vaccines against infection with ExPEC, and may further comprise one or more additional bioconjugates.
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