Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Patrick Burke0
Scott Jeffrey0
Philip Wilson Howard0
Date of Patent
July 18, 2017
0Patent Application Number
151826490
Date Filed
June 15, 2016
0Patent Citations Received
Patent Primary Examiner
Patent abstract
This invention relates to pyrrolobenzodiazepines (PBDs), in particular pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position in each monomer unit, and their inclusion in targeted conjugates. The differing substituent groups may offer advantages in the preparation and use of the compounds, particularly in their biological properties and the synthesis of conjugates, and the biological properties of these conjugates.
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