Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Carsten Rudolph0
Braydon Charles Guild0
Christian Plank0
Frank DeRosa0
Lianne Smith0
Michael Heartlein0
Date of Patent
July 25, 2017
0Patent Application Number
148760710
Date Filed
October 6, 2015
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Pharmaceutical compositions comprising an mRNA-loaded nanoparticle, wherein the mRNA is an in vitro transcribed mRNA and has a coding sequence at least 80% identical to SEQ ID NO: 3, and wherein the mRNA encodes a human cystic fibrosis transmembrane conductance regulator (CFTR) protein comprising the amino acid sequence of SEQ ID NO:1 are provided. The present invention is particularly useful for treating cystic fibrosis.
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