An multi-position adjustable pillow intended to support a user's head, neck, shoulders, lower back, legs, and/or knees is provided. The pillow may include a cover sized to fit around a plurality of support pieces, including a top support piece and one or more removable bottom support pieces. The cover includes an aperture adapted to allow at least a bottom support piece to be inserted or removed. The aperture may be securable by a zipper or other fastening means. The support pieces may be made of a soft material, such as foam. The bottom support pieces may be made of a material that is of greater density and of lower firmness than the top support piece.