Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 7, 2017
Patent Application Number
15656845
Date Filed
July 21, 2017
Patent Citations Received
Patent Primary Examiner
Patent abstract
Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making beta-lactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections.
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