A method for producing scratch-off lottery tickets in a high speed printing line is provided, wherein the printing line includes one or more inkjet printing machines that print lottery tickets on a continuously running paper stock. One or more primer layers are applied to a surface of the paper stock in a defined game play area on each lottery ticket. With the inkjet printing machines game play indicia is printed over the primer layers in the game play area on each lottery ticket at a resolution of at least 600 dpi. The running paper stock is conveyed through the inkjet printing machines at a rate of at least 950 ft./min. The ink jet printing machines use a specially formulated dye-based ink.