Is a
Patent attributes
Patent Applicant
Patent Jurisdiction
Patent Number
Patent Inventor Names
Paolo Costantino0
Francesco Berti0
Date of Patent
November 28, 2017
Patent Application Number
14267248
Date Filed
May 1, 2014
Patent Citations Received
Patent Primary Examiner
Patent abstract
Capsular saccharides derived from serogroups W135 and Y of Neisseria meningitidis have altered levels of O-acetylation at the 7 and 9 positions of their sialic acid residues, and can be used to make immunogenic compositions. Relative to unmodified native saccharides, derivatives of the invention are preferentially selected during conjugation to carrier proteins, and conjugates of the derivatives show improved immunogenicity compared to native polysaccharides.
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