Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Samson Tom0
Alla Danilkovitch0
Christopher Ton0
Date of Patent
November 28, 2017
0Patent Application Number
141382650
Date Filed
December 23, 2013
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides preparations of MSCs with important therapeutic potential. The MSC cells are non-primary cells with an antigen profile comprising less than about 1.25% CD45+ cells (or less than about 0.75% CD45+), at least about 95% CD105+ cells, and at least about 95% CD166+ cells. Optionally, MSCs of the present preparations are isogenic and can be expanded ex vivo and cryopreserved and thawed, yet maintain a stable and uniform phenotype. Methods are taught here of expanding these MSCs to produce a clinical scale therapeutic preparations and medical uses thereof.
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