US Patent 9834786 Nuclease-mediated targeting with large targeting vectors
Patent 9834786 was granted and assigned to Regeneron Pharmaceuticals on December, 2017 by the United States Patent and Trademark Office.
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Patent abstract
Compositions and methods are provided for making one or more targeted genetic modifications at a target genomic locus by employing homologous recombination facilitated by single or double-strand break at or near the target genomic locus. Compositions and methods for promoting efficiency of homologous recombination between an LTVEC and a target genomic locus in prokaryotic or eukaryotic cells using engineered nucleases are also provided.
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Patent Inventor Names
David Frendewey0
David M. Valenzuela0
George D. Yancopoulos0
Ka-Man Venus Lai0
Wojtek Auerbach0
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US Patent 09834786 Nuclease-mediated targeting with large targeting vectors US Patent 9834786 Nuclease-mediated targeting with large targeting vectors
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Patent Number
098347860
Patent Number
98347860
Edits on 25 Sep, 2022
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Infobox
Is a
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
098347860
Date of Patent
December 5, 2017
0Patent Application Number
138702800
Date Filed
April 25, 2013
0Patent Primary Examiner
Edits on 16 Jan, 2022
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Infobox (+9 properties)
US Patent 09834786 Nuclease-mediated targeting with large targeting vectors
Infobox
Is a
Patent applicant
Current assignee
Patent jurisdiction
Patent number
09834786
Date of patent
December 5, 2017
Patent application number
13870280
Date Filed
April 25, 2013
Patent primary examiner
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